Chemotherapy regimens

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Chemotherapy regimens are often identified with acronyms, identifying the agents used in combination. Unfortunately, the letters used are not consistent across regimens, and in some cases (for example, "BEACOPP") the same letter is used to represent two different treatments. Because of this, there is not a naming standard for chemotherapy regimens, and this page merely represents commonly used conventions.

The term "Induction regimens" refers to a chemotherapy regimen which is used for the initial treatment of a disease.

Name Components Example of uses, and other notes
FOLFOX Fluorouracil, leucovorin (folinic acid), and oxaliplatin Colorectal cancer
VAD Vincristine, Adriamycin (doxorubicin), dexamethasone Multiple myeloma
Thal/Dex Thalidomide, dexamethasone Multiple myeloma
CHOP Cyclophosphamide, doxorubicin (hydroxydoxorubicin), vincristine (Oncovin), prednisone Non-Hodgkin lymphoma
CHOP-R CHOP + rituximab B cell non-Hodgkin lymphoma
COP or CVP Cyclophosphamide, vincristine (Oncovin), and prednisone Non-Hodgkin lymphoma in patients with history of cardiovascular disease
m-BACOD Methotrexate, bleomycin, doxorubicin (Adriamycin), cyclophosphamide, vincristine (Oncovin), dexamethasone (Decadron) Non-Hodgkin lymphoma
ProMACE-CytaBOM Prednisone, doxorubicin (adriamycin), cyclophosphamide, etoposide, cytarabine, bleomycin, vincristine (Oncovin), methotrexate, leucovorin Non-Hodgkin lymphoma
COPP Cyclophosphamide, Oncovin (vincristine), procarbazine and prednisone Non-Hodgkin lymphoma
MACOP-B Methotrexate, leucovorin, doxorubicin (Adriamycin), cyclophosphamide, vincristine (Oncovin), prednisone, bleomycin Non-Hodgkin lymphoma
ProMACE-MOPP Methotrexate, doxorubicin (Adriamycin), cyclophosphamide, etoposide + MOPP Non-Hodgkin lymphoma
MOPP (medicine) Mechlorethamine, vincristine (oncovin), procarbazine, prednisone Hodgkin's lymphoma
ABVD Adriamycin, bleomycin, vinblastine, dacarbazine Hodgkin's lymphoma
BEACOPP Bleomycin, etoposide, Adriamycin (doxorubicin), cyclophosphamide, Oncovin (vincristine), procarbazine, prednisone Hodgkin's lymphoma
Stanford V Doxorubicin (Adriamycin), mechlorethamine, bleomycin, vinblastine, vincristine (Oncovin), etoposide (VP-16), prednisone Hodgkin's lymphoma
ECF Epirubicin, cisplatin, fluorouracil Gastric cancer and oesophageal cancer
BEP Bleomycin, etoposide, platinum (cisplatin) Testicular cancer
PCV Procarbazine, lomustine (CCNU), vincristine Brain tumors

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Chemotherapeutic agents/Antineoplastic agents (L01) edit - Chemotherapy regimens
Alkylating agents:

Nitrogen mustards: ( Chlorambucil, Chlormethine, Cyclophosphamide, Ifosfamide, Melphalan). Nitrosoureas: ( Carmustine, Fotemustine, Lomustine, Streptozocin). Platinum: ( Carboplatin, Cisplatin, Oxaliplatin, BBR3464). Busulfan, Dacarbazine, Mechlorethamine, Procarbazine, Temozolomide, ThioTEPA, Uramustine

Antimetabolites:

Folic acid: ( Methotrexate, Pemetrexed, Raltitrexed). Purine: ( Cladribine, Clofarabine, Fludarabine, Mercaptopurine, Tioguanine). Pyrimidine: ( Capecitabine). Cytarabine, Fluorouracil, Gemcitabine

Plant alkaloids:

Taxane: ( Docetaxel, Paclitaxel). Vinca: ( Vinblastine, Vincristine, Vindesine, Vinorelbine).

Cytotoxic/antitumor antibiotics:

Anthracycline family: (Daunorubicin, Doxorubicin, Epirubicin, Idarubicin, Mitoxantrone, Valrubicin). Bleomycin, Hydroxyurea, Mitomycin

Topoisomerase inhibitors:

Topotecan, Irinotecan, Podophyllum: ( Etoposide, Teniposide).

Monoclonal antibodies:

Alemtuzumab, Bevacizumab, Cetuximab, Gemtuzumab, Panitumumab, Rituximab, Trastuzumab

Photosensitizers:

Aminolevulinic acid, Methyl aminolevulinate, Porfimer sodium, Verteporfin

Kinase inhibitors:

Dasatinib, Erlotinib, Gefitinib, Imatinib, Lapatinib, Nilotinib, Sorafenib, Sunitinib, Vandetanib (ZD6474)

Other:

Alitretinoin, Altretamine, Amsacrine, Anagrelide, Arsenic trioxide, Asparaginase, Bexarotene, Bortezomib, Denileukin diftitox, Estramustine, Hydroxycarbamide, Pentostatin, Masoprocol, Mitotane, Pegaspargase, Tretinoin