Cetylpyridinium chloride

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Cetylpyridinium chloride is a cationic quaternary ammonium compound in some types of mouthwash such as Crest Pro-Health®, Scope®, Reach ACT®, Cēpacol®, Viadent®, Oasis®, Dr. Fresh®, swish®, BreathRX®, and BetaCell®, toothpastes such as Crest Sensitivity® and Crest Plus Scope®, Cēpacol® lozenges and throat sprays, anti-snore throat sprays (Breathe Right®, Rite Aid, CVS, Walgreens, etc.), Oasis® moisturizing mouth spray, BreathRX® breath spray, and SinoFresh® and Ayr No-Drip Sinus® nasal sprays. It is an antiseptic that kills bacteria and other microorganisms. It has been shown to be effective in preventing dental plaque and reducing gingivitis. It has also been used as an ingredient in certain pesticides. However, this ingredient has also been shown (according to WebMD,^[1] eMedicine,^[2] and Amazon.com and Drugstore.com reviews of Crest Pro-Health® rinse product) to cause brown stains between the teeth.

1 Synonyms
2 Physical and chemical properties
3 Toxicology and Pharmacology
4 References
5 External links

[edit] Synonyms

Cetylpyridinium chloride is also known as 1-palmitylpyridinium chloride, C16-alkylpyridinium chloride, 1-hexadecylpyridinium chloride, acetoquat CPC, aktivex, ammonyx CPC, cecure, ceepryn chloride, cepacol, ceprim, cepacol chloride, cetafilm, cetamium, dobendan, halset, ipanol, medilave, mercocet, merothol, pionin B, pristacin, pyrisept.

[edit] Physical and chemical properties

Cetylpyridinium chloride has the molecular formula C₂₁H₃₈NCl and is a white powder at room temperature. It has a melting point of 77 degrees when anhydrous or 80-83 degrees in its monohydrate form. It is insoluble in acetone, acetic acid,or ethanol but is otherwise freely soluble.