Cephalic flexure

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Cephalic flexure
Brain of human embryo of four and a half weeks, showing interior of fore-brain. (Cephalic flexure visible at center top.)
Gray's subject #184 737
Dorlands/Elsevier f_09/12368378

The first flexure of the embryonic brain appears in the region of the mid-brain, and is named the ventral cephalic flexure.

By means of it the fore-brain is bent in a ventral direction around the anterior end of the notochord and fore-gut, with the result that the floor of the fore-brain comes to lie almost parallel with that of the hind-brain.

This flexure causes the mid-brain to become, for a time, the most prominent part of the brain, since its dorsal surface corresponds with the convexity of the curve.

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This article was originally based on an entry from a public domain edition of Gray's Anatomy. As such, some of the information contained herein may be outdated. Please edit the article if this is the case, and feel free to remove this notice when it is no longer relevant.

Mammalian development of embryo and development and fetus (some dates are approximate - see Carnegie stages) - edit - discuss

Week 1: Zygote | Morula | Blastula/Blastomere/Blastosphere | Archenteron/Primitive streak | Blastopore | Allantois | Trophoblast (Cytotrophoblast | Syncytiotrophoblast | Gestational sac)

Week 2: Yolk sac | Vitelline duct | Bilaminar disc

Week 3: Hensen's node | Gastrula/Gastrulation | Trilaminar embryo Branchial arch (1st) | Branchial pouch | Meckel's cartilage | Somite/Somitomere | Germ layer (Ectoderm, Endoderm, Mesoderm, Chordamesoderm, Paraxial mesoderm, Intermediate mesoderm, Lateral plate mesoderm)

Histogenesis and Organogenesis

Circulatory system: Primitive atrium | Primitive ventricle | Bulbus cordis | Truncus arteriosus | Ostium primum | Foramen ovale | Ductus venosus | Ductus arteriosus | Aortic arches | Septum primum | Septum secundum | Cardinal veins

Nervous system: Neural development/Neurulation | Neurula | Neural folds | Neural groove | Neural tube | Neural crest | Neuromere (Rhombomere) | Notochord | Optic vesicles | Optic stalk | Optic cup

Digestive system: Foregut | Midgut | Hindgut | Proctodeum | Rathke's pouch | Septum transversum

Urinary/Reproductive system: Urogenital folds | Urethral groove | Urogenital sinus | Kidney development (Pronephros | Mesonephros | Ureteric bud | Metanephric blastema) | Fetal genital development (Wolffian duct | Müllerian duct | Gubernaculum | Labioscrotal folds)

Glands: Thyroglossal duct

Uterine support: Placenta | Umbilical cord (Umbilical artery, Umbilical vein, Wharton's jelly) | Amniotic sac (Amnion, Chorion)

Limb development: Limb bud | Apical Ectodermal Ridge/AER