Centrophenoxine

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Centrophenoxine
Systematic (IUPAC) name
?
Identifiers
CAS number	51-68-3
ATC code	?
PubChem	4039
Chemical data
Formula	C12H16ClNO3
Mol. weight	257.713
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Centrophenoxine (also called Meclofenoxate, and formerly sold under the brand name Lucidril®) is a drug used to treat the symptoms of senile dementia and Alzheimer's Disease. It is a compound of two biochemicals: dimethylaminoethanol (DMAE) and parachlorophenoxyacetate (pCPA). DMAE is a natural substance, found especially in fish, and also produced in the human brain. pCPA is a synthetic compound that resembles to a variety of plant hormones called auxins.

Like DMAE, it is a precursor to the neurotransmitter acetylcholine and may increase levels of this chemical in the CNS. It is reported to improve memory and general cognition.

It is also used off-label as a nootropic, often combined with a racetam drug such as piracetam.

[edit] Side Effects & Contraindications

Possible side effects may include nausea or mild dizziness. People with severely high blood pressure or convulsive disorders such as epilepsy should avoid Centrophenoxine. ^[1] Large doses may cause tight jaw clenching.