Ceforanide
From Wikipedia, the free encyclopedia
Ceforanide
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Systematic (IUPAC) name | |
(6R,7R)-7-{[2-[2-(aminomethyl)phenyl]acetyl]amino}-3- {[1-(carboxymethyl)tetrazol-5-yl]sulfanylmethyl}-8-oxo- 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
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Identifiers | |
CAS number | 60925-61-3 |
ATC code | J01DC11 |
PubChem | 43507 |
DrugBank | APRD00853 |
Chemical data | |
Formula | C20H21N7O6S2 |
Mol. weight | 519.556 g/mol |
Pharmacokinetic data | |
Bioavailability | ? |
Protein binding | 80.6% |
Metabolism | Nil |
Half life | 2.6 to 2.98 hours |
Excretion | Renal |
Therapeutic considerations | |
Pregnancy cat. |
? |
Legal status | |
Routes | Intramuscular |
Ceforanide is a second-generation cephalosporin antibiotic.
[edit] External links
- Crowle A, Sbarbaro J, May M (1988). "Effects of isoniazid and of ceforanide against virulent tubercle bacilli in cultured human macrophages.". Tubercle 69 (1): 15-25. PMID 3140456.
- Campoli-Richards D, Lackner T, Monk J (1987). "Ceforanide. A review of its antibacterial activity, pharmacokinetic properties and clinical efficacy.". Drugs 34 (4): 411-37. PMID 3315624.
- Cone L, Barton S, Woodard D (1987). "Treatment of scleroma with ceforanide.". Arch Otolaryngol Head Neck Surg 113 (4): 374-6. PMID 3814386.
Cephalosporin Antibiotics (J01D) edit | ||
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First Generation: |
Cefacetrile, Cefadroxil, Cefalexin, Cefaloglycin, Cefalonium, Cefaloridine, Cefalotin, Cefapirin, Cefatrizine, Cefazaflur, Cefazedone, Cefazolin, Cefradine, Cefroxadine, Ceftezole |
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Second Generation: |
Cefaclor, Cefamandole, Cefonicid, Ceforanide, Cefotiam, Cefprozil, Cefuroxime, Cefuzonam |
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Third Generation: |
Cefcapene , Cefdaloxime, Cefdinir, Cefditoren, Cefetamet, Cefixime, Cefmenoxime, Cefodizime, Cefoperazone, Cefotaxime, Cefpimizole, Cefpiramide, Cefpodoxime, Cefsulodin, Ceftazidime, Cefteram, Ceftibuten, Ceftiofur, Ceftiolene, Ceftizoxime, Ceftriaxone, Latamoxef |
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Fourth Generation: |
Cefclidine, Cefepime, Cefetecol, Cefluprenam, Cefoselis, Cefozopran, Cefpirome, Cefquinome |