Ceforanide

From Wikipedia, the free encyclopedia

Ceforanide chemical structure
Ceforanide
Systematic (IUPAC) name
(6R,7R)-7-{[2-[2-(aminomethyl)phenyl]acetyl]amino}-3-
{[1-(carboxymethyl)tetrazol-5-yl]sulfanylmethyl}-8-oxo-
5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Identifiers
CAS number 60925-61-3
ATC code J01DC11
PubChem 43507
DrugBank APRD00853
Chemical data
Formula C20H21N7O6S2 
Mol. weight 519.556 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding 80.6%
Metabolism Nil
Half life 2.6 to 2.98 hours
Excretion Renal
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes Intramuscular

Ceforanide is a second-generation cephalosporin antibiotic.

[edit] External links

  • Crowle A, Sbarbaro J, May M (1988). "Effects of isoniazid and of ceforanide against virulent tubercle bacilli in cultured human macrophages.". Tubercle 69 (1): 15-25. PMID 3140456.
  • Campoli-Richards D, Lackner T, Monk J (1987). "Ceforanide. A review of its antibacterial activity, pharmacokinetic properties and clinical efficacy.". Drugs 34 (4): 411-37. PMID 3315624.
  • Cone L, Barton S, Woodard D (1987). "Treatment of scleroma with ceforanide.". Arch Otolaryngol Head Neck Surg 113 (4): 374-6. PMID 3814386.


Cephalosporin Antibiotics (J01D) edit
First Generation:

Cefacetrile, Cefadroxil, Cefalexin, Cefaloglycin, Cefalonium, Cefaloridine, Cefalotin, Cefapirin, Cefatrizine, Cefazaflur, Cefazedone, Cefazolin, Cefradine, Cefroxadine, Ceftezole

Second Generation:

Cefaclor, Cefamandole, Cefonicid, Ceforanide, Cefotiam, Cefprozil, Cefuroxime, Cefuzonam

Third Generation:

Cefcapene , Cefdaloxime, Cefdinir, Cefditoren, Cefetamet, Cefixime, Cefmenoxime, Cefodizime, Cefoperazone, Cefotaxime, Cefpimizole, Cefpiramide, Cefpodoxime, Cefsulodin, Ceftazidime, Cefteram, Ceftibuten, Ceftiofur, Ceftiolene, Ceftizoxime, Ceftriaxone, Latamoxef

Fourth Generation:

Cefclidine, Cefepime, Cefetecol, Cefluprenam, Cefoselis, Cefozopran, Cefpirome, Cefquinome