Cefacetrile
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Cefacetrile
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| Systematic (IUPAC) name | |
| (6R,7R)-3-(acetyloxymethyl)-7-[(2-cyanoacetyl)amino]- 8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2- carboxylic acid |
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| Identifiers | |
| CAS number | 10206-21-0 |
| ATC code | J01DB10 |
| PubChem | 91562 |
| Chemical data | |
| Formula | C13H13N3O6S |
| Mol. weight | 339.325 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Protein binding | 23 to 38% |
| Metabolism | ? |
| Half life | 1.2 hours |
| Excretion | Renal (72%) |
| Therapeutic considerations | |
| Pregnancy cat. |
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| Legal status | |
| Routes | Intravenous, intramuscular |
Cefacetrile (INN, also spelled cephacetrile) is a broad-spectrum first generation cephalosporin antibiotic effective in Gram-positive and Gram-negative bacterial infections. It is a bacteriostatic antibiotic. Cefacetrile is marketed under the tradenames Celospor®, Celtol®, and Cristacef®.
| Cephalosporin Antibiotics (J01D) edit | ||
|---|---|---|
| First Generation: |
Cefacetrile, Cefadroxil, Cefalexin, Cefaloglycin, Cefalonium, Cefaloridine, Cefalotin, Cefapirin, Cefatrizine, Cefazaflur, Cefazedone, Cefazolin, Cefradine, Cefroxadine, Ceftezole |
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| Second Generation: |
Cefaclor, Cefamandole, Cefonicid, Ceforanide, Cefotiam, Cefprozil, Cefuroxime, Cefuzonam |
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| Third Generation: |
Cefcapene , Cefdaloxime, Cefdinir, Cefditoren, Cefetamet, Cefixime, Cefmenoxime, Cefodizime, Cefoperazone, Cefotaxime, Cefpimizole, Cefpiramide, Cefpodoxime, Cefsulodin, Ceftazidime, Cefteram, Ceftibuten, Ceftiofur, Ceftiolene, Ceftizoxime, Ceftriaxone, Latamoxef |
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| Fourth Generation: |
Cefclidine, Cefepime, Cefetecol, Cefluprenam, Cefoselis, Cefozopran, Cefpirome, Cefquinome |
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