CD86

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Structure of human CD86 receptor binding domain
CD86 molecule
Identifiers
Symbol(s)	CD86
Entrez	942
OMIM	601020
RefSeq	[1]
UniProt	[2]
PDB	1NCN
Other data
Locus	Chr. 3 q21

The protein CD86 is a molecule which provides a costimulatory signal necessary for T cell activation and survival. It is also known as B7.2. Its principal mode of action is by binding to CD28. Along with CD80, these molecules provide the necessary stimuli to prime T cells against antigens presented by antigen-presenting cells.