CD11c
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integrin, alpha X (complement component 3 receptor 4 subunit)
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| Identifiers | |
| Symbol(s) | ITGAX CD11C |
| Entrez | 3687 |
| OMIM | 151510 |
| RefSeq | NM_000887 |
| UniProt | P20702 |
| Other data | |
| Locus | Chr. 16 p11.2 |
CDC11c is a type I transmembrane protein found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst; expressed in hairy cell leukemias, acute nonlymphocytic leukemias, and some B-cell chronic lymphocytic leukemias.
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