Catherine Barton
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Catherine Barton (1679-?) was Isaac Newton's half-niece, and had a relationship with Charles Montagu, 1st Earl of Halifax after his wife's death in 1698. An excerpt of an uncharacteristically warm letter from Newton survives, regarding her contraction of smallpox: "Pray let me know by your next how your [face is] and if your fevour (sic) be going. Perhaps warm milk from ye Cow may [help] to abate it. I am Your loving Unkle (sic), Is. Newton."
A fictional Barton has a small role in Neal Stephenson's novel "The System of the World," the final installment in Stephenson's "Baroque Cycle."