Cannabidiol

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Cannabidiol
Systematic (IUPAC) name
2-((1S,6S)-3-methyl-6-(prop-1-en-2-yl) cyclohex-2-enyl)-5-pentylbenzene-1,3-diol
Identifiers
CAS number	13956-29-1
ATC code	noentry
PubChem	644019
DrugBank	none
Chemical data
Formula	C₂₁H₃₀O₂
Mol. weight	314.46
SMILES	CCCCCC(C=C1O)=CC(O)=C1[C@]2 (C=C(C)CC[C@]2([H])C(C)=C)[H]
Physical data
Melt. point	66 °C (151 °F)
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Cannabidiol, also known as CBD, is a non-psychoactive cannabinoid found in the hemp plant Cannabis sativa.

CBD alone is not psychoactive, but it appears to reduce the euphoric effect of THC (which is an isomer of cannabidiol) and add a sedative quality. It may decrease the rate of THC clearance from the body, perhaps by interfering with the metabolism of THC in the liver. Medically, it appears to relieve convulsion, inflammation, anxiety, and nausea. CBD has a greater affinity for the CB2 receptor than for the CB1 receptor. It is perceived to have more effect on the body.

[edit] Medicinal use

In April 2005, Canadian authorities approved the marketing of Sativex, a mouth spray for multiple sclerosis to alleviate pain. Sativex contains tetrahydrocannabinol together with cannabidiol. It is marketed in Canada by GW Pharmaceuticals.