Butyrophenone

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Butyrophenones are a class of pharmaceutical drugs used to treat various pyschiatric disorders such as schizophrenia.

Examples include:

• Haloperidol, the most widely used drug in this class
• Droperidol, often used for neuroleptanalgesic anesthesia and sedation in intensive care treatment
• Benperidol, the most potent commonly used antipsychotic (~ 200 times more potent as chlorpromazine)
• Triperidol, a highly potent antipsychotic (100 times more potent than chlorpromazine)
• Melperone, a weakly potent antipsychotic, in Europe commonly used for treatment of insomnia, confusional states, psychomotor agitation, and delirium, particular in geriatric patients