Brimonidine

From Wikipedia, the free encyclopedia

Brimonidine chemical structure
Brimonidine
Systematic (IUPAC) name
5-bromo-N- (4,5-dihydro-1H-imidazol-2-yl) quinoxalin-6-amine
Identifiers
CAS number 59803-98-4
ATC code S01EA05
PubChem 2435
DrugBank APRD00034
Chemical data
Formula C11H10BrN5
Mol. weight 292.135 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life 2 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

Brimonidine (bri-MOE-ni-deen ) is a drug used to treat glaucoma. It acts via decreasing aqueous humor synthesis.

Brimonidine is an alpha receptor agonist.


Antiglaucoma preparations and miotics (S01E) edit
Sympathomimetics:

Apraclonidine, Brimonidine, Clonidine, Dipivefrine, Epinephrine

Parasympathomimetics:

Aceclidine, Acetylcholine, Carbachol, Demecarium, Echothiophate, Fluostigmine, Neostigmine, Paraoxon, Physostigmine, Pilocarpine

Carbonic anhydrase inhibitors:

Acetazolamide, Brinzolamide, Diclofenamide, Dorzolamide, Methazolamide

Beta blocking agents:

Befunolol, Betaxolol, Carteolol, Levobunolol, Metipranolol, Timolol

Prostaglandin analogues:

Bimatoprost, Latanoprost, Travoprost, Unoprostone

Other agents:

Dapiprazole, Guanethidine