Bisabolol

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α-(-)-Bisabolol
Bisabolol
Bisabolol
Bisabolol
Chemical name (R)-6-methyl-2-((R)-4-methylcyclohex-3-enyl)hept-5-en-2-ol
Chemical formula C15H26O
Molecular mass 222.37 g/mol
CAS number (–): [23089-26-1]
(±): [515-69-5]
Density 0.92 g/cm3
Melting point  ? °C
Boiling point 153 °C at 12 mmHg
SMILES C/C(C)=C/CC[C@](O)(C)[C@@]1([H])CC=C(C)CC1
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Bisabolol, or more formally α-(-)-bisabolol or also as levomenol, is a natural monocyclic sesquiterpene alcohol. It is a colorless viscous oil that is the primary constituent of the essential oil from German chamomile (Matricaria recutita). It is almost insoluble in water and glycerin, but well soluble in ethanol. The enantiomer, α-(+)-bisabolol, is also found naturally but is rare. Synthetic bisabolol is usually a racemic mixture of the two, α-(±)-bisabolol.

Bisabolol has a weak sweet floral aroma and is used in various fragrances. It has also been used for hundreds of years in cosmetics because of its perceived skin healing properties. Bisabolol is known to have anti-irritant, anti-inflammatory and anti-microbial properties.

A structurally related compound known as β-bisabolol (CAS# [15352-77-9]) differs only in the position of the tertiary alcohol functional group.

β-Bisabolol
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β-Bisabolol


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