Benzonatate

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Image:Benzonatate.png
Benzonatate
Systematic (IUPAC) name
2-[2-[2-[2-[2-[2-[2-[2- (2-methoxyethoxy) ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethyl4-butylaminobenzoate
Identifiers
CAS number	104-31-4
ATC code	R05 DB01
PubChem	7699
DrugBank	APRD00629
Chemical data
Formula	C₃₀H₅₃NO₁₁
Mol. weight	603.742 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	3- 8 hours
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

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Benzonatate or 2,5,8,11,14,17,20,23,26-nonaoxaoctacosan-28-yl para-butylaminobenzoate is a non-narcotic oral antitussive (cough suppressant) drug which works by anesthetizing the tissues of the lungs and pleura responsible for the cough reflex. It is chemically related to other ester anesthetics such as procaine. According to the Medicine.net article, it has an anesthetic (numbing) action similar to that of benzocaine and "numbs" the stretch sensors in the lungs, and it is the stretching of these sensors with breathing that causes the cough. It's not related to opioids or dextromethorphan. Brand name Tessalon Perles.