Benznidazole

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Benznidazole
Systematic (IUPAC) name
N-benzyl-2-(2-nitroimidazol-1-yl)acetamide
Identifiers
CAS number	22994-85-0
ATC code	P01CA02
PubChem	31593
Chemical data
Formula	C12H12N4O3
Mol. weight	260.249 g/mol
Pharmacokinetic data
Bioavailability	High
Metabolism	Hepatic
Half life	12 hours
Excretion	Renal and fecal
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	Oral

Benznidazole (INN, marketed by Hoffman-La Roche under the trade names Rochagan® and Radanil®) is an antiparasitic medication used in the treatment of Chagas disease.

[edit] Side effects

The side effects most commonly associated with benznidazole therapy are rash and gastrointestinal symptoms such as nausea. Rarely, peripheral neuropathy may present after prolonged treatment.

[edit] External links

• (Portuguese) Rochagan® [Patient Information] (PDF). Hoffmann-La Roche. Retrieved on 2006-11-27.