Benperidol

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Benperidol (1-[1-[4-(4-fluorophenyl)-4-oxo-butyl]-4-piperidyl]-3H-benzoimidazol-2-one, MW: 381.443, MF: C22H24FN3O2) is butyrophenone derivative. It is an antipsychotic, used for the treatment of schizophrenia, but it is primarily used to control deviant, antisocial sexual behaviour. Benperidol was discovered at Janssen Pharmaceutica in 1961.

[edit] References

  • Bobon J, Collard J, Lecoq R, Benperidol and promazine: a "double blind" comparative study in mental geriatrics, Acta Neurol Belg. 1963 Oct;63:839-43.
  • Murray MA, Bancroft JH, Anderson DC, Tennent TG, Carr PJ., Endocrine changes in male sexual deviants after treatment with anti-androgens, oestrogens or tranquillizers, J Endocrinol. 1975 Nov;67(2):179-88.


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