Aschoff bodies

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Aschoff bodies or Aschoff nodules are painless nodules present in rheumatic fever. They are Aschoff cell granulomas with a fibrinoid necrotic centre found in the myocardium surrounding blood vessels, and other regions of the body. Myocytes in the myocardium can merge with the Aschoff cells to form giant cells of Aschoff. In addition, there are leukocytes, lymphocytes, eosinophils and plasma cells. The Aschoff bodies were discovered by the German pathologist Ludwig Aschoff.

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