Talk:Arp2/3 complex
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Arp2/3 complex has been listed as a good article under the good-article criteria. If you can improve it further, please do. |
Hey, I am not sure if the article is that good yet. I am planning to keep improving it though. --Splette 15:14, 27 February 2006 (UTC)
I think it should say that in the barbed-branching model arp2/3 associates with the pointed end. I couldn't access the article.
amulekii
- Hi Amulekii, no that appears to be wrong. Just as written in the article in the barbed-branching model arp2/3 associates with the barbed end. Here is a good article from Biochem J, freely accessible: Signalling to actin assembly via the WASP-family proteins and the Arp2/3 complex In the article they summarize the existing models: "Despite the popularity of the dendritic-nucleation model, data obtained by other groups have led to the development of an alternative barbed-end branching model. Pantaloni et al. proposed that activated Arp2/3 complex binds to the barbed end of the actin filament, rather than at the side, and that the rate of Arp2/3-mediated actin polymerization is proportional to the number of free barbed ends, not the total length of the actin mother filament." I hope this clears things up a bit. Thanks for contacting me on my talk page about it. --Splette
Talk 13:14, 18 May 2006 (UTC)
Oh yeah. I got you. I should have looked more carefully at the pictures you provided. Amulekii 21:37, 18 May 2006 (UTC)
Shouldn't it say Wiskott-Aldrich Syndrome Protein family instead of Wiskott-Aldrich Syndrome family protein? Amulekii 21:43, 18 May 2006 (UTC)
