Angelo Mosso

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Angelo Mosso (30 May 1846 - 24 November 1910), 19th century Italian physiologist, who created the first crude neuroimaging technique by recording the pulsation of the human cortex in patients with skull defects following neurosurgical procedures. From his findings that these pulsations change during mental activity, he inferred that during mental activities blood flow increases to the brain. Though crude, this inference is the basis for the more refined neuroimaging techniques of FMRI and PET, essential to neuroscience research today.

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