Angela Vincent

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Angela Vincent is a professor at Somerville College of Oxford University. She is the head of a research group, which is located in the Institute of Molecular Sciences and working on a wide range of biological disciplines encompassing molecular biology, biochemistry, cellular immunology and intracellular neurophysiology. The group's research is focused on autoimmune and genetic disorders of the neuromuscular junction and peripheral motor nerves. The principal autoimmune diseases studied are myasthenia gravis, the Lambert-Eaton myasthenic syndrome and acquired neuromyotonia.

Her contributions are mainly on the roles of antibodies directed against ion channel at the nerve-muscle junction in the pathogenesis of above mentioned diseases. She has demonstrated that transfer of these antibodies across the placenta from the mother to the unborn baby in the uterus can cause developmental abnormalities. She has also worked on the principal gene mutations causing nerve-muscle disorders.

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