Anecortave

From Wikipedia, the free encyclopedia

Anecortave chemical structure
Anecortave
Systematic (IUPAC) name
[2-[(8R,10S,13S,14R,17R)-
17-hydroxy-10,13-dimethyl-3-oxo-
2,6,7,8,12,14,15,16-octahydro-
1H-cyclopenta[a]phenanthren-17-yl]-
2-oxo-ethyl] acetate
Identifiers
CAS number 7753-60-8
ATC code S01XA16
PubChem 111332
DrugBank ?
Chemical data
Formula C23H30O5
Mol. weight 386.48
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status

Schedule 4 (Aust)

Routes intravitreal depot injection

Anecortave (rINN) (IPA: [ænəˈkɔteɪv]) is a novel angiogenesis inhibitor used in the treatment of the exudative (wet) form of age-related macular degeneration. Although based on a steroid nucleus, it possesses little glucocorticoid activity. It is marketed by Alcon as anecortave acetate for depot suspension under the trade name Retaane.


[edit] External links