Amrinone

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Amrinone chemical structure
Amrinone
Systematic (IUPAC) name
5-amino-3,4'-bipyridin-6(1H)-one
Identifiers
CAS number 60719-84-8
ATC code C01CE01
PubChem 3698
Chemical data
Formula C10H9N3O 
Mol. weight 187.198 g/mol
Pharmacokinetic data
Bioavailability n/a
Protein binding 10 to 49%
Metabolism Hepatic
Half life 5 to 8 hours
Excretion Renal (63%) and fecal (18%)
Therapeutic considerations
Pregnancy cat.

C(US)

Legal status

-only(US)

Routes Intravenous

Amrinone (INN) or inamrinone, trade name Inocor®, is a pyridine phosphodiesterase inhibitor. It is used in the treatment of congestive heart failure.

Selective Phosphodiesterase inhibitors (C01CE, G04BE)edit
PDE1:

Vinpocetine

PDE2:

EHNA

PDE3:

Amrinone, Bucladesine, Enoximone, Milrinone

PDE4:

Rolipram

PDE5:

Sildenafil, Tadalafil, Vardenafil