Amrinone
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Amrinone
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Systematic (IUPAC) name | |
5-amino-3,4'-bipyridin-6(1H)-one | |
Identifiers | |
CAS number | 60719-84-8 |
ATC code | C01CE01 |
PubChem | 3698 |
Chemical data | |
Formula | C10H9N3O |
Mol. weight | 187.198 g/mol |
Pharmacokinetic data | |
Bioavailability | n/a |
Protein binding | 10 to 49% |
Metabolism | Hepatic |
Half life | 5 to 8 hours |
Excretion | Renal (63%) and fecal (18%) |
Therapeutic considerations | |
Pregnancy cat. |
C(US) |
Legal status |
℞-only(US) |
Routes | Intravenous |
Amrinone (INN) or inamrinone, trade name Inocor®, is a pyridine phosphodiesterase inhibitor. It is used in the treatment of congestive heart failure.
Selective Phosphodiesterase inhibitors (C01CE, G04BE)edit | ||
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PDE1: | ||
PDE2: | ||
PDE3: |
Amrinone, Bucladesine, Enoximone, Milrinone |
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PDE4: | ||
PDE5: |