Alexander Fleming BSRC
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Biomedical Sciences Research Center "Alexander Fleming" is a government-supported institution in Vari, Athens, Greece, which develops research programmes at the cutting edge of modern biomedical sciences. Current research interests involve the development and characterisation of mouse models of lymphoid and epithelial malignancies and inflammatory disorders, the study of molecular mechanisms of oncogenesis, the analysis of basic mechanisms of transcription and the characterization of molecular mechanisms that underlie behaviour and neuronal stem cell development. The Centre is equipped with state of the art facilities which include a FACS-Vantage cell sorter, a protein chemistry core facility with a Biacore 3000 biosensor and a Finnigan LCQDECA electrospray ionization-ion trap LC-mass spectrometer, a core genomics facility with a ScanArray Express microarray scanner (Packard BioScience) and a ChipWriter DNA microarray spotter (Bio-Rad) and a state of the art specific pathogen free mouse facility with an extensive record in the generation of transgenic and conventional and tissue specific knock-out animals. BSRC "Alexander Fleming" was recently appointed coordinator of MUGEN NoE [1], a consortium of 24 European organizations constituting a Network of Excellence on 'Functional Genomics in mutant mouse models as tools to investigate the complexity of human immunological disease' (6th Framework Program, 2005-2009).
