Talk:AKT

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What does Akt stand for? Danielkueh 07:18, 11 June 2006 (UTC)

Akt is not an abbreviation; it is the name of the gene encoding a particular protein: Akt or Akt1. The name Akt stems from the name of the transforming retrovirus that was first cloned from a translocation into the akt allele; the virus form of the gene was called "v-akt"; the normal, cellular form of Akt, unmutated, was for a short type called "c-akt". Then the normal, unmutated gene was simply called "Akt." Once it was discovered that there are three members to the Akt family, Akt was renamed "Akt1". However, it is usally simply called Akt, whereas the family members "Akt2" and "Akt3" are always referenced with the number. Gacggt 19:10, 4 June 2006 (UTC)

As Akt was originally identified as the oncogene in the transforming retrovirus, AKT8.

Thanks a lot for the info. Greatly appreciated. Danielkueh 21:38, 18 June 2006 (UTC)

Involvement of Forkhead Transcription Factors (FoxO and FKHR1), CREB and YAP in Akt survival signalling. I think, the following should be added to this page. Further, Akt can directly inactivate some caspases (most notably Caspase-9).