Acetamide

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Acetamide
100
Systematic name Acetamide
Ethanamide
Molecular formula C2H5NO
Molar mass 59.07 g/mol
CAS number [60-35-5]
Density 1.16 g/cm³
Solubility in Water 200 g/100 ml
Melting point 81 °C
Boiling point 222 °C
SMILES CC(=O)N
Hazards
MSDS External MSDS
EU classification Harmful (Xn)
Carc. Cat. 3
NFPA 704
Image:nfpa h3.png Image:nfpa f1.png Image:nfpa r1.png
R-phrases R40
S-phrases S2, S36/37
Except where noted otherwise, data are given for
materials in their standard state (at 25 °C, 100 kPa)
Infobox disclaimer and references

Acetamide (or acetic acid amide or ethanamide), CH3CONH2, the amide of acetic acid, is a white crystalline solid in pure form. It is produced by dehydrating ammonium acetate. It is used as a plasticizer and in the synthesis of many other organic compounds.

Acetamide is not extremely combustible, but releases irritating fumes when ignited. It is toxic by inhalation (of dust), ingestion, skin and eye contact. Skin or eye contact may cause redness and pain.

The derivative N,N-dimethylacetamide (DMA), which has two methyl groups replacing the amine protons, is used as a solvent.

Recent work on the Robert C. Byrd Green Bank Telescope has resulted in the discovery of several organic (carbon-based) compounds near the center of the Milky Way galaxy. Acetamide has been detected. This is particularly important as Acetamide has a peptide bond, the essential bond between amino acids in proteins. This supports the theory that organic molecules that can lead to life (as we know it on Earth) can form in space.

[edit] Cancer link

Acetamide has been found to cause cancer in laboratory animals. It is classified in Group 2B "possible human carcinogen" by the IARC.

[edit] External links