Acetamide
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Acetamide | ||||
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Systematic name | Acetamide Ethanamide |
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Molecular formula | C2H5NO | |||
Molar mass | 59.07 g/mol | |||
CAS number | [60-35-5] | |||
Density | 1.16 g/cm³ | |||
Solubility in Water | 200 g/100 ml | |||
Melting point | 81 °C | |||
Boiling point | 222 °C | |||
SMILES | CC(=O)N | |||
Hazards | ||||
MSDS | External MSDS | |||
EU classification | Harmful (Xn) Carc. Cat. 3 |
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NFPA 704 |
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R-phrases | R40 | |||
S-phrases | S2, S36/37 | |||
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
Acetamide (or acetic acid amide or ethanamide), CH3CONH2, the amide of acetic acid, is a white crystalline solid in pure form. It is produced by dehydrating ammonium acetate. It is used as a plasticizer and in the synthesis of many other organic compounds.
Acetamide is not extremely combustible, but releases irritating fumes when ignited. It is toxic by inhalation (of dust), ingestion, skin and eye contact. Skin or eye contact may cause redness and pain.
The derivative N,N-dimethylacetamide (DMA), which has two methyl groups replacing the amine protons, is used as a solvent.
Recent work on the Robert C. Byrd Green Bank Telescope has resulted in the discovery of several organic (carbon-based) compounds near the center of the Milky Way galaxy. Acetamide has been detected. This is particularly important as Acetamide has a peptide bond, the essential bond between amino acids in proteins. This supports the theory that organic molecules that can lead to life (as we know it on Earth) can form in space.
[edit] Cancer link
Acetamide has been found to cause cancer in laboratory animals. It is classified in Group 2B "possible human carcinogen" by the IARC.