Aceclidine
From Wikipedia, the free encyclopedia
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Aceclidine
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| Systematic (IUPAC) name | |
| 1-azabicyclo[2.2.2]oct-8-yl acetate | |
| Identifiers | |
| CAS number | 827-61-2 (or 6109-70-2 [HCl]) |
| ATC code | S01EB08 |
| PubChem | 1979 |
| Chemical data | |
| Formula | C9H15NO2 |
| Mol. weight | 169.221 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status |
℞ Prescription only |
| Routes | Ocular |
Aceclidine (INN) (Glaucostat®, Glaunorm®, Glaudin®) is a parasympathomimetic miotic agent used in the treatment of narrow angle glaucoma. It decreases intraocular pressure.
[edit] Mechanism of Action
Aceclidine acts primarily on the muscarinic receptor.
[edit] Side effects
Side effects of aceclidine include increased salivation, bradycardia (in excessive doses).
[edit] References
- ACECLIDINE CHLORHYDRATE [Article in French] Biam. Last update: 2 September 1999. Accessed 13 September 2005 (UTC)
- ACECLIDINE (АЦЕКЛИДИН) [Article in Russian] ViDAL 2005. Accessed 13 September 2005.
| Antiglaucoma preparations and miotics (S01E) edit | ||
|---|---|---|
| Sympathomimetics: |
Apraclonidine, Brimonidine, Clonidine, Dipivefrine, Epinephrine |
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| Parasympathomimetics: |
Aceclidine, Acetylcholine, Carbachol, Demecarium, Echothiophate, Fluostigmine, Neostigmine, Paraoxon, Physostigmine, Pilocarpine |
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| Carbonic anhydrase inhibitors: |
Acetazolamide, Brinzolamide, Diclofenamide, Dorzolamide, Methazolamide |
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| Beta blocking agents: |
Befunolol, Betaxolol, Carteolol, Levobunolol, Metipranolol, Timolol |
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| Prostaglandin analogues: |
Bimatoprost, Latanoprost, Travoprost, Unoprostone |
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| Other agents: |
Dapiprazole, Guanethidine |
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