4-Hydroxy-5-methoxydimethyltryptamine

From Wikipedia, the free encyclopedia

4-Hydroxy-5-methoxydimethyltryptamine, or 4,5-HO-MeO-DMT, is the 4-hydroxy counterpart of 5-MeO-DMT.

It is a psychedelic tryptamine but very little is known about it. The only report of it in the chemical literature was a paper published by Marc Julia's group at the Pasteur Institute in 1965. They only reported the synthesis and physical properties of the compound and has never been documented to be explored in any other way.

It cites a 10 step synthesis from ortho-vanillin. However, Alexander Shulgin has explained that it could be possible to cultivate 4,5-HO-MeO-DMT in psilocybin mushrooms by adding 5-MeO-DMT to the growing substrate of the fungus. Though this method has never been explored with 4,5-HO-MeO-DMT it has had success with changing DIPT and DPT to 4-HO-DIPT / 4-HO-DPT, both of which had never before been found in nature.

In the cases of DPT and DIPT the mushrooms yielded only 4-HO-DPT/DIPT instead of psilocybin (4-HO-DMT). Not only rendering a new chemical but rendering the fungus it self completely legal because of its absence of psilocybin. Theoretically, this method would 4-hydroxylize any tryptamine added to the substrate, opening the possibility of synthesizing not yet discovered tryptamines.

[edit] External links



Psychedelic tryptamines edit

4-Acetoxy-DET, 4-Acetoxy-DIPT, 4,5-HO-MeO-DMT, α-ET, α-MT, Baeocystin, Bufotenin, DET, DIPT, DMT, DPT, EIPT, Ethocin, Ethocybin, Iprocin, MET, MIPT, 5-MeO-α-ET, 5-MeO-α-MT, 5-MeO-DALT, 5-MeO-DET, 5-MeO-DIPT, 5-MeO-DMT, 5-MeO-DPT, 5-MeO-MIPT, Miprocin, Norbaeocystin, Psilocin, Psilocybin