1-(3-Chlorophenyl)piperazine
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| 1-(3-Chlorophenyl)piperazine | |
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| Chemical name | 1-(3-Chlorophenyl)piperazine |
| Other names | 1-(m-Chlorophenyl)piperazine, mCPP |
| Chemical formula | C10H13ClN2 |
| Molecular mass | 196.676 g/mol |
| CAS number | [6640-24-0] |
| Density | ? g/cm3 |
| Melting point | ? °C |
| SMILES | C1CN(CCN1)C2=CC(=CC=C2)Cl |
| Disclaimer and references | |
1-(3-Chlorophenyl)piperazine (or meta-chlorophenylpiperazine, mCPP) is a piperazine-based 5-HT receptor agonist that has been used as a challenge drug in MDMA research. In the mid-2000s, it has shown up in legal alternatives to illegal stimulants in New Zealand, and pills sold as ecstasy in Europe and the United States.
mCPP is known to induce headaches in humans,[1][2] and has been used for testing potential anti-migraine medications.[3]
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[edit] Legal status
In the US: unscheduled
In New Zealand: unscheduled
In Denmark: Banned [4]
[edit] See also
- Benzylpiperazine (BZP)
- Trifluoromethylphenylpiperazine (TFMPP)
[edit] References
- ^ Leone M, Attanasio A, Croci D, Filippini G, D'Amico D, Grazzi L, Nespolo A, Bussone G. The serotonergic agent m-chlorophenylpiperazine induces migraine attacks: A controlled study. Neurology. 2000 Jul 12;55(1):136-9.
- ^ Martin RS & Martin GR. Investigations into migraine pathogenesis: time course for effects of m-CPP, BW723C86 or glyceryl trinitrate on appearance of Fos-like immunoreactivity in rat trigeminal nucleus caudalis (TNC). Cephalalgia 2001; 21:46–52. London. ISSN 0333-10245
- ^ Petkov VD, Belcheva S, Konstantinova E. Anxiolytic effects of dotarizine, a possible antimigraine drug. Methods Find Exp Clin Pharmacol. 1995 Dec;17(10):659-68.
- ^ Erowid.org
[edit] External links
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