Talk:ΔF508

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[edit] Merger

I do not think this article should be merged simply because CF isn't the only effect of this gene. When other 'weaker' mutations are present along with it, it can cause Congenital Absence of the Vas Deferens, even without the other effects of CF (I should clarify this in the article). I think there is enough material for a good article on this gene specifically (google for it if you doubt this) and I think that this specific genetic cause of CF, as detailed in this article, would make the CF article a bit crowded. --TexasDex 00:59, August 15, 2005 (UTC)

Perhaps a more general article on the genetic causes of CF would be more suitable. This is currently a hot research topic and there is plenty to discuss about it that wouldn't fit well into the main article. --ImmortalGoddezz 02:11, 15 August 2005 (UTC)

I'll probably get around to that eventually. --TexasDex 04:22, September 7, 2005 (UTC)

I'm still not sure if one mutation should have its own article. Even if CAVD is germane only to d508, this fact could be mentioned on the CF page itself, given that d508 causes the majority of CF cases. I do not disagree with TexasDex that CFTR should not have its own article (it has already), but d508 is just one of the 100s of documented mutations in that gene. JFW | T@lk 16:27, 26 September 2005 (UTC)

It should probably be merged with CFTR (gene) --WS 13:22, 12 January 2006 (UTC)

It makes more sense to merge it with the CF page. It is by far the most common mutation resulting in clinically significant CF. JFW | T@lk 14:24, 12 January 2006 (UTC)

How about merging both CFTR and this into Genetic Causes of Cystic Fibrosis? Between the two articles there's an awful lot of detail that could make a substantial sub-article, but might be a bit too big for a simple section.--TexasDex