(-)-2-β-Carbomethoxy-3-β-(4-fluorophenyl)tropane naphthalenedisulfonate

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(-)-2-β-Carbomethoxy-3-β-(4-fluorophenyl)tropane naphthalenedisulfonate (CFT) is a dopamine reuptake inhibitor structurally similar to cocaine. It is around 3-10x more potent than cocaine and lasts around 7 times longer based on animal studies.

CAS# 50370-56-4

CFT was discovered in 1980 during research into the mechanism of action of cocaine.

Radiolabelled forms of CFT have been used in humans and animals to map the distribution of dopamine transporters in the brain. CFT is about as addictive as cocaine in animal studies, but is taken less often due to its longer duration of action. Potentially this could make it a suitable drug to be used as a substitute for cocaine, in a similar manner to how methadone is used as a substitute for opiates in treating addiction.

CFT has no history of abuse in humans, and is not specifically illegal anywhere in the world, but would probably be considered a controlled substance analogue of cocaine in the USA and Australia, due to its similar effects.